While still a student, he made his Wigmore Hall recital debut in the Schubertiade series and appeared at the Cheltenham and Brighton Festivals.
On the concert platform, he has sung with the Cleveland Orchestra under von Dohnanyi, the Bournemouth Symphony under Hickox, the Monteverdi Choir and Orchestra under Eliot Gardiner, the San Francisco Symphony under Tilson Thomas, the Rotterdam Philharmonic under Gergiev, Les Musiciens du Louvre under Minkowski, the London Symphony Orchestra under Rattle and the Orchestra of the Eighteenth Century under Frans Brüggen. He has appeared in concert at the Salzburg and Edinburgh Festivals under Norrington and Mackerras. He has recorded for Deutsche Grammophon, Decca, BMG, Philips, Collins, Hyperion and EMI.
He made his début as Idamantes (Idomeneo) for Welsh National Opera, Scottish Opera and the Bavarian State Opera. For the Monnaie, Brussels he has sung Tamino (Die Zauberflöte) under David Robertson and David (Die Meistersinger von Nürnberg) under Antonio Pappano. For the Salzburg Festival he has sung in Mitridate under Roger Norrington, and Hylas (Les Troyens). For the Netherlands Opera he has sung Telemaco (Il ritorno d'Ulisse in patria) in both Amsterdam and Sydney and for the Bavarian State Opera Ferrando (Cosi fan tutte), Acis and Galatea and Il ritorno d'Ulisse in patria. He sang Fidelio with the Glyndebourne Festival at the Chatelet under Rattle, Don Giovanni for the Ruhr Triennale, Alcina in San Francisco, Tamino at the Teatro Real, Madrid and Hyllas (Handel’s Hercules) in Aix-en-Provence. For the Royal Opera, Covent Garden he has sung the Simpleton (Boris Godunov), Ferdinand (Ades’ The Tempest) and Almaviva. He sang an acclaimed Madwoman (Curlew River) at the 2005 Edinburgh Festival.
Toby Spence has established strong links with both English National Opera and the Paris Opera. With ENO he has sung Almaviva (The Barber of Seville), Oronte (Alcina), Narciso (Il turco in Italia), Fenton (Falstaff), Ferrando (Cosi fan tutte) and Tamino. For the Paris Opera he has sung in Billy Budd, Les Boreades, Guillaume Tell, Alcina, Die Meistersinger von Nürnberg and Katja Kabanova. Future engagements include Tom Rakewell (The Rake’s Progress) for the Paris Opera, Ottavio for the Bavarian State Opera, David (Die Meistersinger) in Geneva and Los Angeles, Ferrando for the Hamburg Opera, Almaviva, Kudryash, The Tempest and Ramiro for the Royal Opera, Covent Garden, and Tamino and The Tempest in Santa Fe.