He is especially admired for his performances of repertoire from the 20th and 21st centuries, and receives regular invitations from major festivals and orchestras in Europe, the USA, Canada, Australia, New Zealand and Japan. Of his many recordings, Grisey's Les Espaces Acoustiques has been singled out for particular praise and won both the Diapason d'or de l'année 1999 and the Grand Prix de l'Académie Charles Cros, which he won again in 2008 for three other works. His more recent recordings include works by Hugues Dufourt (winner Diapason d'Or and Choc du Monde de la Musique), and Harrison Birtwistle's Theseus Game for Deutsche Grammophon, a piece he premiered in Duisburg and conducted at the Southbank Centre, BBC Proms, Huddersfield Festival, Lucerne International Festival and in Berlin.
A regular guest conductor with the Tonhalle Orchester Zürich, other orchestras include BBC Symphony, BBC Scottish Symphony, Scottish Chamber Orchestra, BBC National Orchestra of Wales, Philharmonia, Ulster, RTE National Symphony, Royal Northern Sinfonia, Luxembourg Philharmonic, Oslo Philharmonic, Göteborgs Symfoniker, Odense Symphony Orchestra, Norrbotten NEO, Orchestre Philharmonique de Radio France, Orchestre de Paris, Saarbrucken Radio Symphony, Athens State Orchestra, Montreal Symphony, Seoul Philharmonic, Tokyo Philharmonic, Orchestra della RAI Torino, Accademia Nationale di Santa Cecilia Rome, Teatro Carlo Felice Genova, Ensemble Intercontemporain, London Sinfonietta, Birmingham Contemporary Music Group, Bit 20, Bodo Sinfonietta, Contrechamps Geneve, the Asko Schoenberg Ensemble, I Pomeriggi Musicale, Luxembourg Philharmonic, Bilbao Symphony Orchestra, Polish National Radio Symphony and the Philharmonia’s Music of Today series and Ensemble Modern.
He conducted his BBC Proms debut in 2001, and has also appeared at the Aldeburgh, Bath International, Holland, Strasbourg Musica, Oslo Ultima, Monte Carlo Le Printemps des Arts, Nice Manca, Paris Ircam Agora, Radio-France Présences, Perth and Sydney festivals.
In January 2001 he was awarded Chevalier dans l'Ordre des Arts et des Lettres by the French Minister of Culture.