Sergey has performed with orchestras such as the Berliner Philharmoniker, Royal Concertgebouw Orchestra, Orchestre National de France, Orchestre de Paris, London Symphony Orchestra, London Philharmonic Orchestra, Philharmonia Orchestra, NHK Symphony in Tokyo, Munich Philharmonic and the Tonhalle Orchestra in Zurich.

Following his début with the Cleveland Orchestra in 2004, Sergey has subsequently appeared with the New York Philharmonic and Kurt Masur, the Boston Symphony and Bernard Haitink, the Los Angeles Philharmonic and Stéphane Denève, the Philadelphia Orchestra and Charles Dutoit, and the San Francisco Symphony and Michael Tilson Thomas. In August 2005 Sergey performed at the Ravinia and Blossom Festivals and in 2006 made his début at the Mostly Mozart Festival performing the Beethoven concerto with Osmo Vänskä.

Sergey has performed at the Royal Festival Hall in London with the Philharmonia Orchestra conducted by Christoph von Dohnanyi, Esa Pekka Salonen, Rafael Fruhbeck de Burgos, Alexander Lazarev and Tugan Sokhiev. With the London Philharmonic Orchestra Sergey performed the Bach Double Concerto with Anne-Sophie Mutter, the Sibelius concerto with Jukka Pekka Saraste and the Khachaturian concerto on a major North American tour in March 2006. In January 2011 he made his London début with the London Symphony Orchestra performing Shostakovich’s second concerto conducted by Valery Gergiev.

Since December 2002 Sergey has performed regularly with the BBC Philharmonic Orchestra, including a Proms début in 2005 conducted by Vassily Sinaisky and regular concerts subsequently with Gianandrea Noseda.

Sergey works regularly with Valery Gergiev and the Mariinsky Theatre Orchestra in St Petersburg and at the Mikkeli Festival in Finland. His 2010-11 season included début performances with the Dresden Staatskapelle, Tokyo Metropolitan Symphony, National Symphony Orchestra Washington, Rotterdam Philharmonic as well as the Melbourne and Sydney Symphony Orchestras. Other highlights included the Munich Philharmonic with Thomas Hengelbrock, Orchestre National de Belgique with James Gaffigan, Swedish Radio Symphony with Susanna Mälkki, and the Berg concerto with the Bournemouth Symphony Orchestra with Kirill Karabits.

Sergey’s 2011-12 season includes concerts with the Bamberg Symphoniker and Herbert Blomstedt, Rundfunk Symphonieorchester Berlin with Juraj Valcuha, Orchestre de Paris with Andris Nelsons, his début in China with the National Centre of Performing Arts Orchestra for New Year’s concerts conducted by Lorin Maazel and the world premièree of a new concerto by Arthur Aharonian with the Amsterdam Sinfonietta.

With his sister Lusine Khachatryan Sergey has performed recitals at the Wigmore Hall, Alte Oper Frankfurt, the National Auditorium in Madrid, Carnegie Hall, Theatre des Champs Elysees in Paris, and the Concertgebouw in Amsterdam. In 2011-12 they will perform recitals in the series of Chicago University Presents, Detroit Chamber Music Society, Cite de la Musique in Paris, the Palais des Beaux Arts in Brussels, the Luxembourg Philharmonie, Alice Tully Hall in New York and Herbst Theater in San Francisco.

His recording of the Sibelius concerto was released by Naïve Classique in October 2003, followed by a double Shostakovich concerto disc with the Orchestre National de France conducted by Kurt Masur, a recording of the Shostakovich and Cesar Franck sonatas for violin and piano in February 2008 and most recently the complete Sonatas and Partitas for solo violin by J.S. Bach.

Sergey plays the 1740 ‘Ysaye’ Guarneri violin on kind loan from the Nippon Music Foundation.